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Interesting questions. I suspect that part of the asymmetry has to do with our tracing responsibility for the drug-induced actions to the agent's decision to take drugs. In the case of blameworthy actions, we think they made a bad decision to take drugs knowing it might lead them to do something bad (akin to drunk driving). In the case of praiseworthy artistic creations, we think they made a good decision to take drugs knowing it might enhance their artistic abilities (or at least release them).

I think the asymmetry you mention is only apparent. The appearance derives from the fact that your examples (praise for doped *artists*, no blame for intoxicated *agents*) are not homogeneous (and/or not clearly defined). The appearance of asymmetry disappears once you look at better defined and homogeneous examples. Ceteris paribus, you can praise and blame doped artists for good and bad artworks done under the influence of drugs, whereas you should not praise nor blame people for, say, making politically appropriate/inappropriate comments under the influence of the same drugs. No asymmetry is left, once the kind of activity at stake and the kind of evaluation are the same. In my opinion, then, there is no asymmetry between praise and blame for doped actions, though there are of course differences between the (positive and negative) evaluation of actions or activities in which rational capacities are relevant and the evaluation of actions where these capacities are not relevant. Where rationality is relevant, the influence of (rationality-impairing) drugs may (ceteris paribus) affect praise and blame. Where rationality is not relevant for the good result of the performance - or possibly even an obstacle to it - the influence of (rationality-impairing) drugs may not affect the evaluation of the performance.

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