Toronto researchers report preliminary success in treating depression with electrode implant treatment. See here. This is a sample:
"Guided by Dr. Mayberg's previous research findings on the critical role of Cg25 in mood regulation and antidepressant drug response, we hypothesized that if we could re-tune this abnormally functioning circuit by way of a surgical intervention that uses electrical stimulation, we could produce clinical benefit in patients with refractory depression," says Dr. Lozano.
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"Our study shows that areas of the brain that are on overdrive in patients with severe depression can be pinpointed, turned down and brought to a more normal level of activity using electrical stimulation," adds Dr. Lozano. "This in turn can lead to a lifting of depression in certain patients."